Normally people have the idea as to what happens in the causes of vitiligo but they are less certain as to what happens in this disease. We are aware of the fact that the pigment cells do not function in the white patches though a few survive in the skin and then in the hair follicles. There are a number of theories which exist to explain the pigment destruction – the much famous one is the autoimmune theory that means the human body’s immune system attacks the pigment cells.
Of late it has been discovered that the genes in human beings enacts the vital part to predispose few patients to vitiligo in particular those who are laced with other autoimmune diseases such as thyroid disease or are swathed with family disease. The exploration gets the autoimmune theory strengthened.
The other theories proposed include the ones like neuronal theory that lets the nerves in human skin get implicated in the destruction of the pigment cells. Additionally the higher level of hydrogen peroxide that happens to be toxic to the cells of pigments traced in the patients’ skin with vitiligo.
Environment also affects the disease like the stress, changes in the hormonal, puberty and childbirth, etc might shoot the disease upwards. And these environmental factors enact the vital role in disease’s progress.
Great read.