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Diseases like Vitiligo

Vitiligo is a chronic disease which causes depigmentation of skin in the form

disease-like-vitiligo

disease-like-vitiligo

of white patches. Vitiligo occurs when melanocytes that are responsible for skin pigmentation, die or unable to perform their function. Segmented vitiligo is a common form of vitiligo. Vitiligo has some confusion with other diseases like nevus depigmentosus, white scars and hypopigmentation, pityriases Alba, idiopathic guttate hypomelanosis and pigmentation.

Nevus depigmentosus is a stable disease which is limited to a small area. It appears in the form of white spots on body. It increases as the growth of body increases. The main cause of this disease is the irregularity in the function of melanocytes which produce little pigments. White scars  and hypopigmentation is another skin disease which looks like vitiligo. In this disease scars appear due to injury. Scars may be white or colored; it depends on type of injury. Scars can be a result of physical, chemical or inflammatory as acne.  Melanocytes may destroy or damage due to  injury. Therefore white scars and hypopigmentation occurs.

Pityriases Alba is also a skin disease which is frequently present in children. It mostly comes into views in dry weather and the people having dry skin. It generally appears as dry scales, pale patches on the face. Pityriases Alba can be treated by moisturizing cream. Normally, boys are affected by this disease. It takes place due to activity of melanocytes abnormally low.  Idiopathic guttate hypomelanosis has also confusion with vitiligo.

Generally, women suffer from this disease. It appears in the form of round shape on skin. Parts of body having exposure of sun light, experience idiopathic guttate hypomelanosis like face, forearms, shoulders. A medical treatment that involves removal of damage tissues and cells known as biopsies is used to treat that problem but as a result thickness of skin reduces. Protection from the sun is very important in this disease. It is commonly observed in people having fair complexion.

Pigmentation is a phenomenon of coloring. .Pigment means color. In biological term it means “a material that give color to the cells of human beings, animals and plants’’. It determines the color of eyes, hair and skin. Many conditions can change the level of pigment. Sometimes level of pigments increases due to excessive tanning and pregnancy known as hyper pigmentation. Sometimes level of pigment decreases known as hypopigmentation due to vitiligo, leprosy, albinism and many others.

Diseases like vitiligo have little existence but vitiligo is most common now. Vitiligo does not damage the health. But it destroys the personality badly and creates psychological problems. It can come out in any age, race and in any gender.

Is Indoor Tanning Addictive?

Is indoor tanning addictive? To find out the answer of this question,

tanning-bed

tanning-bed

aresearch is conducted in New York. A questionnaire base research has been held which resulting that indoor tanning may addict the young people. Indoor tanning bed may also prone anxiety and substance abuse (a drug which is used to change the mood) problem. Actually, indoor tanning bed provides the same ultraviolet rays that are emitted from sun and you can control the rays according to your need. As we knowvery well, there is no alternative of natural thing. Many vitiligo patients also use indoor tanning along with psoralins.

421 college students of northeastern United States were assigned a task to complete a questionnaire about indoor tanning habits, anxiety, substance abuse problem and demographics. The results were not favorable because 30.6% students met mCAGE that stands for cut down, annoyed, guilty and eye opener. 23 indoor tanning sessions also conducted in the last year. Both groups were more tanned than those who were not tanning addictive. Indoor tanning addict usually experience anxiety and mood disorder. They use alcohol and marijuana to calm themselves.

Vitiligo Treatment with Tacrolimus and Excimer Laser

Combined Treatment with Tacrolimus and Excimer Laser in Vitiligo

tacrolimus-and-excimer-laser

tacrolimus-and-excimer-laser

Tacrolimus is an immunosuppressive drug whose main use is after allogeneic organ transplant to reduce the activity of patient`s immune system and so lower the risk of organ rejection. It is also used in
the treatment of eczema and vitiligo. Recently it has also been used in the treatment of segmental vitiligo in children, especially on face.

Excimer laser is the form of ultraviolet laser which is used in surgery of eye and dermatological treatment. For the treatment of vitiligo, dermatologists combined the tacrolimus and excimer laser. A study published in Journal Watch Dermatology about the combined treatment of tacrolimus with excimer laser has shown significant results. These results are far better than expectations. This research can bring repigmentation in affected skin by vitiligo, especially in those areas which are difficult to treat such as fingers and bone prominences.
Dermatologists conducted an intra-individual study in which one side of body works as a control. They treated 43 patches in 14 patients affected by symmetrical vitiligo. One side of body is exposed either by excimer laser or tacrolimus ointment and on the other side combined treatment was established. Combined treatment showed the results of 70% in the form of extensive repigmentation and laser therapy showed 20% extensive repigmentation. Whatever the results, the satisfactory level is high in this technique.

Treatment of Vitiligo with Autologous Cell Suspension

Treatment of Vitiligo with Autologous Cell Suspension A study “treatment of

autologous-cell-suspension

autologous-cell-suspension

Vitiligo with Autologous cell Suspension” was published in Journal Watch dermatology, October 27, 2004. This research was held in India. It was the study of segmented Vitiligo and focal Vitiligo treated by cell suspension with melanocytes and Keratenocytes cell transplantation. Using cell suspension with non cultured melanocytes which is injected into the blister of depigmented lesions, gave 85% positive response in the form of regimentation.
Dermatologists transplanted the autologous cell suspension into lesions of 49 cases of segmental Vitiligo and 25 of focal Vitiligo. The results were 84% of the studied cases of segmental Vitiligo and 73% of focal Vitiligo. And during the following 5 years, there has not been seen loss of pigments. It is very useful and simpler technique than UV phototherapy and transplant of cultured melanocytes. But it is sophisticated research to be done outside the major hospital setup. A hospital with sophisticated lab is very significant for the isolation of cell suspension.

PABA and its use in Vitiligo

Vitiligo affects the 1% of population without discrimination of race, sex, age

and background. Victims of Vitiligo lost their little pigments before the 20 years old. It does not physically affect the body but may cause the psychological problems. To eliminate this, research work is going on.

PABA is an organic compound that stands for Para amino benzoic acid was under consideration. PABA is a nutrition supplement. The deficiency of PABA in body originate irritability, fatigue, depression, weeping eczema, premature hardening of skin and loss of pigments (Vitiligo). The medical literature has a lot of information about PABA in various disciplines of medical. It is also useful for the treatment of Vitiligo.

Many researches have been published about PABA and its use in Vitiligo. In 1942, a publishing research claimed success without including any control group. But this research has not scientific significance.

PABA has no side effects and covers the safety issues from the range of hyper sensitivity to the liver damage and skin depigmentation. However, it is not still proved beneficial for children, nursing women, pregnant women and the patients of liver and kidney.